Mouse Zygotes Respond to Severe Sperm DNA Damage by Delaying Paternal DNA Replication and Embryonic Development

Mouse zygotes do not activate apoptosis in response to DNA damage. We previously reported a unique form of inducible sperm DNA damage termed sperm chromatin fragmentation (SCF). SCF mirrors some aspects of somatic cell apoptosis in that the DNA degradation is mediated by reversible double strand bre...

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Bibliografske podrobnosti
Main Authors: Gawecka, Joanna E., Marh, Joel, Ortega, Michael, Yamauchi, Yasuhiro, Ward, Monika A., Ward, W. Steven
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576397/
https://ncbi.nlm.nih.gov/pubmed/23431372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056385
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