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Smad ubiquitination regulatory factor 2 expression is enhanced in hypertrophic scar fibroblasts from burned children
Transforming growth factor-β1 (TGF-β1) plays a key role in hypertrophic scar formation. A lot of studies have shown that TGF-β1 stimulates fibroblast proliferation, collagen production, and α-smooth muscle actin (α-SMA) expression, inhibits matrix degradation and eventually leads to scar formation....
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3576018/ https://ncbi.nlm.nih.gov/pubmed/21920670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.burns.2011.08.012 |
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