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Smad ubiquitination regulatory factor 2 expression is enhanced in hypertrophic scar fibroblasts from burned children

Transforming growth factor-β1 (TGF-β1) plays a key role in hypertrophic scar formation. A lot of studies have shown that TGF-β1 stimulates fibroblast proliferation, collagen production, and α-smooth muscle actin (α-SMA) expression, inhibits matrix degradation and eventually leads to scar formation....

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Sonraí Bibleagrafaíochta
Main Authors: Zhang, Zhi, Finnerty, Celeste C, He, Jing, Herndon, David N
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576018/
https://ncbi.nlm.nih.gov/pubmed/21920670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.burns.2011.08.012
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