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Smad-binding decoy reduces extracellular matrix expression in human hypertrophic scar fibroblasts

The exact mechanisms underlying hypertrophic scarring is yet to be fully understood. However, excessive collagen deposition by fibroblasts has been demonstrated to result in hypertrophic scar formation, and collagen synthesis in dermal fibroblasts is regulated by the transforming growth factor-β1/Sm...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Med Rep
Main Authors: Fan, Chen, El Andaloussi, Samir, Lehto, Taavi, Kong, Kiat Whye, Seow, Yiqi
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7646840/
https://ncbi.nlm.nih.gov/pubmed/33173952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11549
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