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Smad-binding decoy reduces extracellular matrix expression in human hypertrophic scar fibroblasts
The exact mechanisms underlying hypertrophic scarring is yet to be fully understood. However, excessive collagen deposition by fibroblasts has been demonstrated to result in hypertrophic scar formation, and collagen synthesis in dermal fibroblasts is regulated by the transforming growth factor-β1/Sm...
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| Veröffentlicht in: | Mol Med Rep |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
D.A. Spandidos
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7646840/ https://ncbi.nlm.nih.gov/pubmed/33173952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11549 |
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