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Smad-binding decoy reduces extracellular matrix expression in human hypertrophic scar fibroblasts

The exact mechanisms underlying hypertrophic scarring is yet to be fully understood. However, excessive collagen deposition by fibroblasts has been demonstrated to result in hypertrophic scar formation, and collagen synthesis in dermal fibroblasts is regulated by the transforming growth factor-β1/Sm...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Fan, Chen, El Andaloussi, Samir, Lehto, Taavi, Kong, Kiat Whye, Seow, Yiqi
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7646840/
https://ncbi.nlm.nih.gov/pubmed/33173952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11549
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