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Smad-binding decoy reduces extracellular matrix expression in human hypertrophic scar fibroblasts

The exact mechanisms underlying hypertrophic scarring is yet to be fully understood. However, excessive collagen deposition by fibroblasts has been demonstrated to result in hypertrophic scar formation, and collagen synthesis in dermal fibroblasts is regulated by the transforming growth factor-β1/Sm...

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Bibliografische gegevens
Gepubliceerd in:Mol Med Rep
Hoofdauteurs: Fan, Chen, El Andaloussi, Samir, Lehto, Taavi, Kong, Kiat Whye, Seow, Yiqi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7646840/
https://ncbi.nlm.nih.gov/pubmed/33173952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11549
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