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Dynamics and functional differences between dendroaspin and rhodostomin: Insights into protein scaffolds in integrin recognition

Dendroaspin (Den) and rhodostomin (Rho) are snake venom proteins containing a PRGDMP motif. Although Den and Rho have different 3D structures, they are highly potent integrin inhibitors. To study their structure, function, and dynamics relationships, we expressed Den and Rho in Pichia pastoris. The...

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Detalhes bibliográficos
Main Authors: Cheng, Chun-Ho, Chen, Yi-Chun, Shiu, Jia-Hau, Chang, Yao-Tsung, Chang, Yung-Sheng, Huang, Chun-Hau, Chen, Chiu-Yueh, Chuang, Woei-Jer
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575917/
https://ncbi.nlm.nih.gov/pubmed/23033223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2169
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