Engineering of a target site-specific recombinase by a combined evolution- and structure-guided approach

Site-specific recombinases (SSRs) can perform DNA rearrangements, including deletions, inversions and translocations when their naive target sequences are placed strategically into the genome of an organism. Hence, in order to employ SSRs in heterologous hosts, their target sites have to be introduc...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Abi-Ghanem, Josephine, Chusainow, Janet, Karimova, Madina, Spiegel, Christopher, Hofmann-Sieber, Helga, Hauber, Joachim, Buchholz, Frank, Pisabarro, M. Teresa
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Nucleic Acid Enzymes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575804/
https://ncbi.nlm.nih.gov/pubmed/23275541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1308
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki