Involvement of the endogenous hydrogen sulfide/Ca(v)3.2 T-type Ca(2+) channel pathway in cystitis-related bladder pain in mice

BACKGROUND AND PURPOSE: Hydrogen sulfide (H(2)S), generated by enzymes such as cystathionine-γ-lyase (CSE) from L-cysteine, facilitates pain signals by activating the Ca(v)3.2 T-type Ca(2+) channels. Here, we assessed the involvement of the CSE/H(2)S/Ca(v)3.2 pathway in cystitis-related bladder pain...

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Detalhes bibliográficos
Main Authors: Matsunami, Maho, Miki, Takahiro, Nishiura, Kanae, Hayashi, Yuko, Okawa, Yasumasa, Nishikawa, Hiroyuki, Sekiguchi, Fumiko, Kubo, Lisa, Ozaki, Tomoka, Tsujiuchi, Toshifumi, Kawabata, Atsufumi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575789/
https://ncbi.nlm.nih.gov/pubmed/22646666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02060.x
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