Regulation of pluripotency and self-renewal of ES cells through epigenetic-threshold modulation and mRNA pruning

ES cell pluripotency requires bivalent epigenetic modifications of key developmental genes regulated by various transcription factors and chromatin modifying enzymes. How these factors coordinate with one another to maintain the bivalent chromatin state so that ES cells can undergo rapid self-renewa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jia, Junling, Zheng, Xiaobin, Hu, Gangqing, Cui, Kairong, Zhang, Junqi, Zhang, Anying, Jiang, Hao, Lu, Bingwen, Yates, John, Liu, Chengyu, Zhao, Keji, Zheng, Yixian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575637/
https://ncbi.nlm.nih.gov/pubmed/23101626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.09.023
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