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Extended Self-Renewal and Accelerated Reprogramming in the Absence of Kdm5b

Embryonic stem (ES) cell pluripotency is thought to be regulated in part by H3K4 methylation. However, it is unclear how H3K4 demethylation contributes to ES cell function and participates in induced pluripotent stem (iPS) cell reprogramming. Here, we show that KDM5B, which demethylates H3K4, is imp...

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Main Authors: Kidder, Benjamin L., Hu, Gangqing, Yu, Zu-Xi, Liu, Chengyu, Zhao, Keji
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889548/
https://ncbi.nlm.nih.gov/pubmed/24100015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00692-13
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