H2A.Z Facilitates Access of Active and Repressive Complexes to Chromatin in Embryonic Stem Cell Self-renewal and Differentiation

Chromatin modifications have been implicated in the self-renewal and differentiation of embryonic stem cells (ESCs). However, the function of histone variant H2A.Z in ESCs remains unclear. We show that H2A.Z is highly enriched at promoters and enhancers and is required for both efficient self-renewa...

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Detalhes bibliográficos
Main Authors: Hu, Gangqing, Cui, Kairong, Northrup, Daniel, Liu, Chengyu, Wang, Chaochen, Tang, Qingsong, Ge, Kai, Levens, David, Crane-Robinson, Colyn, Zhao, Keji
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570599/
https://ncbi.nlm.nih.gov/pubmed/23260488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.11.003
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