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Extended Self-Renewal and Accelerated Reprogramming in the Absence of Kdm5b
Embryonic stem (ES) cell pluripotency is thought to be regulated in part by H3K4 methylation. However, it is unclear how H3K4 demethylation contributes to ES cell function and participates in induced pluripotent stem (iPS) cell reprogramming. Here, we show that KDM5B, which demethylates H3K4, is imp...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3889548/ https://ncbi.nlm.nih.gov/pubmed/24100015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00692-13 |
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