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Hepatic Stellate Cells Preferentially Induce Foxp3(+) Regulatory T Cells by Production of Retinoic Acid

The liver has long been described as immunosuppressive, although the mechanisms underlying this phenomenon are incompletely understood. Hepatic stellate cells (HSCs), a population of liver nonparenchymal cells, are potent producers of the regulatory T cell (Treg)–polarizing molecules TGF-β1 and all-...

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Autors principals: Dunham, Richard M., Thapa, Manoj, Velazquez, Victoria M., Elrod, Elizabeth J., Denning, Timothy L., Pulendran, Bali, Grakoui, Arash
Format: Artigo
Idioma:Inglês
Publicat: AAI 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575565/
https://ncbi.nlm.nih.gov/pubmed/23359509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201937
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