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Hepatic Stellate Cells Preferentially Induce Foxp3(+) Regulatory T Cells by Production of Retinoic Acid
The liver has long been described as immunosuppressive, although the mechanisms underlying this phenomenon are incompletely understood. Hepatic stellate cells (HSCs), a population of liver nonparenchymal cells, are potent producers of the regulatory T cell (Treg)–polarizing molecules TGF-β1 and all-...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
AAI
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3575565/ https://ncbi.nlm.nih.gov/pubmed/23359509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201937 |
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