Lectins Offer New Perspectives in the Development of Macrophage-Targeted Therapies for COPD/Emphysema

We have previously shown that the defective ability of alveolar macrophages (AM) to phagocytose apoptotic cells (‘efferocytosis’) in chronic obstructive pulmonary disease/emphysema (COPD) could be therapeutically improved using the C-type lectin, mannose binding lectin (MBL), although the exact mech...

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Main Authors: Mukaro, Violet R., Bylund, Johan, Hodge, Greg, Holmes, Mark, Jersmann, Hubertus, Reynolds, Paul N., Hodge, Sandra
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575470/
https://ncbi.nlm.nih.gov/pubmed/23441163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056147
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