Myeloid KLF4 deficiency augments atherogenesis in ApoE-/- mice

OBJECTIVE: To investigate the role of Krüppel-like factor 4 (KLF4), an essential transcriptional regulator of macrophage polarization (M1/M2), in the pathogenesis of atherosclerosis. METHODS AND RESULTS: Despite the acknowledged importance of macrophages in atherosclerosis, the role of M1 (classical...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sharma, Nikunj, Lu, Yuan, Zhou, Guangjin, Liao, Xudong, Kapil, Parul, Anand, Puneet, Mahabeleshwar, Ganapati H, Stamler, Jonathan S., Jain, Mukesh K
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574634/
https://ncbi.nlm.nih.gov/pubmed/23065827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300471
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