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Myeloid KLF4 deficiency augments atherogenesis in ApoE-/- mice
OBJECTIVE: To investigate the role of Krüppel-like factor 4 (KLF4), an essential transcriptional regulator of macrophage polarization (M1/M2), in the pathogenesis of atherosclerosis. METHODS AND RESULTS: Despite the acknowledged importance of macrophages in atherosclerosis, the role of M1 (classical...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3574634/ https://ncbi.nlm.nih.gov/pubmed/23065827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300471 |
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