The Myeloid Transcription Factor KLF2 Regulates the Host Response to Polymicrobial Infection and Endotoxic Shock

Precise control of myeloid cell activation is required for optimal host defense. However, this activation process must be under exquisite control to prevent uncontrolled inflammation. Herein, we identify the Kruppel-like transcription factor 2 (KLF2) as a potent regulator of myeloid cell activation...

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Autores principales: Mahabeleshwar, Ganapati H., Kawanami, Daiji, Sharma, Nikunj, Takami, Yoichi, Zhou, Guangjin, Shi, Hong, Nayak, Lalitha, Jeyaraj, Darwin, Grealy, Robert, White, Mary, McManus, Ross, Ryan, Thomas, Leahy, Patrick, Lin, Zhiyong, Haldar, Saptarsi M., Atkins, G. Brandon, Wong, Hector R., Lingrel, Jerry B., Jain, Mukesh K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103656/
https://ncbi.nlm.nih.gov/pubmed/21565532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.04.014
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