A Myeloid Hypoxia-inducible Factor 1α-Krüppel-like Factor 2 Pathway Regulates Gram-positive Endotoxin-mediated Sepsis

Although Gram-positive infections account for the majority of cases of sepsis, the molecular mechanisms underlying their effects remains poorly understood. We investigated how cell wall components of Gram-positive bacteria contribute to the development of sepsis. Experimental observations derived fr...

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Bibliografiske detaljer
Main Authors: Mahabeleshwar, Ganapati H., Qureshi, Muhammad Awais, Takami, Yoichi, Sharma, Nikunj, Lingrel, Jerry B., Jain, Mukesh K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256857/
https://ncbi.nlm.nih.gov/pubmed/22110137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.312702
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