Myeloid-Specific Deletion of Diacylglycerol Lipase α Inhibits Atherogenesis in ApoE-Deficient Mice

BACKGROUND: The endocannabinoid 2-arachidonoylglycerol (2-AG) is a known modulator of inflammation. Despite its high concentration in vascular tissue, the role of 2-AG in atherogenesis has not yet been examined. METHODS: ApoE-deficient mice were sublethally irradiated and reconstituted with bone mar...

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Veröffentlicht in:PLoS One
Hauptverfasser: Jehle, Julian, Hoyer, Friedrich Felix, Schöne, Benedikt, Pfeifer, Philipp, Schild, Katharina, Jenniches, Imke, Bindila, Laura, Lutz, Beat, Lütjohann, Dieter, Zimmer, Andreas, Nickenig, Georg
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712127/
https://ncbi.nlm.nih.gov/pubmed/26731274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146267
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