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Functional regulation of P-glycoprotein at the blood-brain barrier in proton-coupled folate transporter (PCFT) mutant mice

Folate deficiency has been associated with many adverse clinical manifestations. The blood-brain barrier (BBB), formed by brain capillary endothelial cells, protects the brain from exposure to neurotoxicants. The function of BBB is modulated by multiple ABC transporters, particularly P-glycoprotein....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Xueqian, Cabrera, Robert M., Li, Yue, Miller, David S., Finnell, Richard H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574287/
https://ncbi.nlm.nih.gov/pubmed/23212123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-218495
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