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Inhibition of the Proton-Coupled Folate Transporter (PCFT-SLC46A1) by Bicarbonate and Other Anions

The proton-coupled folate transporter (PCFT) plays a key role in intestinal folate absorption, and loss-of-function mutations in the gene encoding this transporter are the molecular basis for hereditary folate malabsorption. Using a stable transfectant with high expression of PCFT, physiologic level...

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Detalhes bibliográficos
Main Authors: Zhao, Rongbao, Visentin, Michele, Suadicani, Sylvia O., Goldman, I. David
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684825/
https://ncbi.nlm.nih.gov/pubmed/23609145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.085605
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