Targeted STIM deletion impairs calcium homeostasis, NFAT activation, and growth of smooth muscle

The Ca(2+)-sensing stromal interaction molecule (STIM) proteins are crucial Ca(2+) signal coordinators. Cre-lox technology was used to generate smooth muscle (sm)-targeted STIM1-, STIM2-, and double STIM1/STIM2-knockout (KO) mouse models, which reveal the essential role of STIM proteins in Ca(2+) ho...

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Detalhes bibliográficos
Main Authors: Mancarella, Salvatore, Potireddy, Santhi, Wang, Youjun, Gao, Hui, Gandhirajan, Rajesh Kumar, Autieri, Michael, Scalia, Rosario, Cheng, Zhongjian, Wang, Hong, Madesh, Muniswamy, Houser, Steven R., Gill, Donald L.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2013
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574286/
https://ncbi.nlm.nih.gov/pubmed/23159931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-215293
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