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Blockade of NOX2 and STIM1 signaling limits lipopolysaccharide-induced vascular inflammation
During sepsis, acute lung injury (ALI) results from activation of innate immune cells and endothelial cells by endotoxins, leading to systemic inflammation through proinflammatory cytokine overproduction, oxidative stress, and intracellular Ca(2+) overload. Despite considerable investigation, the un...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3561818/ https://ncbi.nlm.nih.gov/pubmed/23348743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65647 |
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