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Efficient Delivery of Cyclic Peptides into Mammalian Cells with Short Sequence Motifs

Cyclic peptides hold great potential as therapeutic agents and research tools, but their broad application has been limited by poor membrane permeability. Here, we report a potentially general approach for intracellular delivery of cyclic peptides. Short peptide motifs rich in arginine and hydrophob...

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Hlavní autoři: Qian, Ziqing, Liu, Tao, Liu, Yu-Yu, Briesewitz, Roger, Barrios, Amy M., Jhiang, Sissy M., Pei, Dehua
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574231/
https://ncbi.nlm.nih.gov/pubmed/23130658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb3005275
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