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Differential Effects of Drug Interventions and Dietary Lifestyle in Developing Type 2 Diabetes and Complications: A Systems Biology Analysis in LDLr−/− Mice

Excess caloric intake leads to metabolic overload and is associated with development of type 2 diabetes (T2DM). Current disease management concentrates on risk factors of the disease such as blood glucose, however with limited success. We hypothesize that normalizing blood glucose levels by itself i...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Radonjic, Marijana, Wielinga, Peter Y., Wopereis, Suzan, Kelder, Thomas, Goelela, Varshna S., Verschuren, Lars, Toet, Karin, van Duyvenvoorde, Wim, van der Werff van der Vat, Bianca, Stroeve, Johanna H. M., Cnubben, Nicole, Kooistra, Teake, van Ommen, Ben, Kleemann, Robert
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2013
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574110/
https://ncbi.nlm.nih.gov/pubmed/23457508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056122
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