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Time-Resolved and Tissue-Specific Systems Analysis of the Pathogenesis of Insulin Resistance

BACKGROUND: The sequence of events leading to the development of insulin resistance (IR) as well as the underlying pathophysiological mechanisms are incompletely understood. As reductionist approaches have been largely unsuccessful in providing an understanding of the pathogenesis of IR, there is a...

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Dettagli Bibliografici
Autori principali: Kleemann, Robert, van Erk, Marjan, Verschuren, Lars, van den Hoek, Anita M., Koek, Maud, Wielinga, Peter Y., Jie, Annie, Pellis, Linette, Bobeldijk-Pastorova, Ivana, Kelder, Thomas, Toet, Karin, Wopereis, Suzan, Cnubben, Nicole, Evelo, Chris, van Ommen, Ben, Kooistra, Teake
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809107/
https://ncbi.nlm.nih.gov/pubmed/20098690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008817
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