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Ablation of the cellular prion protein, PrP(C), specifically on follicular dendritic cells has no effect on their maturation or function
Follicular dendritic cells (FDC) are situated in the primary follicles of lymphoid tissues where they maintain the structural integrity of the B‐lymphocyte follicle, and help to drive immunoglobulin class‐switch recombination, somatic hypermutation and affinity maturation during the germinal centre...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Blackwell Publishing Ltd
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3573278/ https://ncbi.nlm.nih.gov/pubmed/23121447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12031 |
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