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Ablation of the cellular prion protein, PrP(C), specifically on follicular dendritic cells has no effect on their maturation or function

Follicular dendritic cells (FDC) are situated in the primary follicles of lymphoid tissues where they maintain the structural integrity of the B‐lymphocyte follicle, and help to drive immunoglobulin class‐switch recombination, somatic hypermutation and affinity maturation during the germinal centre...

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Detalhes bibliográficos
Main Authors: McCulloch, Laura, Brown, Karen L., Mabbott, Neil A.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573278/
https://ncbi.nlm.nih.gov/pubmed/23121447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12031
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