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Inhibition of Protein-Protein Interaction of HER2-EGFR and HER2–HER3 by a Rationally Designed Peptidomimetic
Protein-protein interactions (PPI) play a crucial role in many biological processes, and modulation of PPI using small molecules to target hot spots has therapeutic value. As a model system we will use PPI of human epidermal growth factor receptors (EGFRs). Among the four EGFRs, EGFR-HER2 and HER2–H...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3572747/ https://ncbi.nlm.nih.gov/pubmed/22731912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07391102.2012.687525 |
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