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The dark energy of proteins comes to light: Conformational entropy and its role in protein function revealed by NMR relaxation
Historically it has been virtually impossible to experimentally determine the contribution of residual protein entropy to fundamental protein activities such as the binding of ligands. Recent progress has illuminated the possibility of employing NMR relaxation methods to quantitatively determine the...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3572299/ https://ncbi.nlm.nih.gov/pubmed/23246280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2012.11.005 |
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