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The dark energy of proteins comes to light: Conformational entropy and its role in protein function revealed by NMR relaxation

Historically it has been virtually impossible to experimentally determine the contribution of residual protein entropy to fundamental protein activities such as the binding of ligands. Recent progress has illuminated the possibility of employing NMR relaxation methods to quantitatively determine the...

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Bibliografiske detaljer
Hovedforfatter: Wand, A. Joshua
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572299/
https://ncbi.nlm.nih.gov/pubmed/23246280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2012.11.005
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