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A surprising role for conformational entropy in protein function
Formation of high-affinity complexes is critical for the majority of enzymatic reactions involving proteins. The creation of the family of Michaelis and other intermediate complexes during catalysis clearly involves a complicated manifold of interactions that are diverse and complex. Indeed, computi...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4052460/ https://ncbi.nlm.nih.gov/pubmed/23478875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/128_2012_418 |
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