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A surprising role for conformational entropy in protein function

Formation of high-affinity complexes is critical for the majority of enzymatic reactions involving proteins. The creation of the family of Michaelis and other intermediate complexes during catalysis clearly involves a complicated manifold of interactions that are diverse and complex. Indeed, computi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wand, A. Joshua, Moorman, Veronica R., Harpole, Kyle W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052460/
https://ncbi.nlm.nih.gov/pubmed/23478875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/128_2012_418
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