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Characterization of internal protein dynamics and conformational entropy by NMR relaxation

Recent studies suggest that the fast timescale motion of methyl-bearing side chains may play an important role in mediating protein activity. These motions have been shown to encapsulate the residual conformational entropy of the folded state that can potentially contribute to the energetics of prot...

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Dettagli Bibliografici
Pubblicato in:Methods Enzymol
Autori principali: Stetz, Matthew A., Caro, José A., Kotaru, Sravya, Yao, Xuejun, Marques, Bryan, Valentine, Kathleen G., Wand, A. Joshua
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364297/
https://ncbi.nlm.nih.gov/pubmed/30638531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2018.09.010
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