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Histone deacetylase inhibitors induce CXCR4 mRNA but antagonize CXCR4 migration
The stromal cell-derived factor-1α SDF-1α (CXCL12)/CXCR4 axis has been linked to poor prognosis in some cancers. As histone deacetylase inhibitors (HDIs) exert antitumor effects by targeting proteins affecting cell migration, we sought to evaluate the effects of the HDIs apicidin, vorinostat, entino...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3571999/ https://ncbi.nlm.nih.gov/pubmed/23192271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.22957 |
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