Histone deacetylase inhibitors induce CXCR4 mRNA but antagonize CXCR4 migration

The stromal cell-derived factor-1α SDF-1α (CXCL12)/CXCR4 axis has been linked to poor prognosis in some cancers. As histone deacetylase inhibitors (HDIs) exert antitumor effects by targeting proteins affecting cell migration, we sought to evaluate the effects of the HDIs apicidin, vorinostat, entino...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Ierano, Caterina, Basseville, Agnes, To, Kenneth K.W., Zhan, Zhirong, Robey, Robert W., Wilkerson, Julia, Bates, Susan E., Scala, Stefania
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2013
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571999/
https://ncbi.nlm.nih.gov/pubmed/23192271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.22957
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares