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Germline polymorphisms in the one-carbon metabolism pathway and DNA methylation in colorectal cancer

Dietary intake of one-carbon nutrients (methyl donors) and germline variants in the one-carbon metabolism genes may influence global DNA methylation level and methylation in promoter CpG islands. In this study, we evaluated the relationship between single nucleotide polymorphisms (SNPs) in the one-c...

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Detalhes bibliográficos
Main Authors: Hazra, Aditi, Fuchs, Charles S., Kawasaki, Takako, Kirkner, Gregory J., Hunter, David J., Ogino, Shuji
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570978/
https://ncbi.nlm.nih.gov/pubmed/19936946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10552-009-9464-2
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