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Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype‐low (CIMP‐low) in colorectal cancer
BACKGROUND: The CpG island methylator phenotype (CIMP or CIMP‐high) with widespread promoter methylation is a distinct epigenetic phenotype in colorectal cancer. In contrast, a phenotype with less widespread promoter methylation (CIMP‐low) has not been well characterised. O‐6‐methylguanine‐DNA methy...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BMJ Group
2007
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2095664/ https://ncbi.nlm.nih.gov/pubmed/17339237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2007.119750 |
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