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Regulation of miR106b cluster through the RB pathway: Mechanism and functional targets
The RB pathway plays a critical role in proliferation control that is commonly subverted in tumor development. However, restoration of RB pathway function can be elicited in many tumor cells by the inhibition of CDK4/6 activity that leads to dephosphorylation of RB and subsequent repression of E2F-m...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3570523/ https://ncbi.nlm.nih.gov/pubmed/23255112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23029 |
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