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Intrinsically disordered proteins and conformational noise: Implications in cancer

Intrinsically disordered proteins, IDPs, are proteins that lack a rigid 3D structure under physiological conditions, at least in vitro. Despite the lack of structure, IDPs play important roles in biological processes and transition from disorder to order upon binding to their targets. With multiple...

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Detalhes bibliográficos
Main Authors: Mahmoudabadi, Gita, Rajagopalan, Krithika, Getzenberg, Robert H., Hannenhalli, Sridhar, Rangarajan, Govindan, Kulkarni, Prakash
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570512/
https://ncbi.nlm.nih.gov/pubmed/23255110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23178
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