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Protein Folding and the Order/Disorder Paradox

Most proteins encoded by the nuclear genome are synthesized in the cytoplasm and fold into precise 3D structures. During synthesis, the nascent polypeptide begins to fold as it traverses the large subunit of the ribosome and is assisted by molecular chaperones in attaining its precise folded/highly...

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Detalhes bibliográficos
Main Authors: Kulkarni, Prakash, Rajagopalan, Krithika, Yeater, David, Getzenberg, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472416/
https://ncbi.nlm.nih.gov/pubmed/21445877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23115
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