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Protein Folding and the Order/Disorder Paradox

Most proteins encoded by the nuclear genome are synthesized in the cytoplasm and fold into precise 3D structures. During synthesis, the nascent polypeptide begins to fold as it traverses the large subunit of the ribosome and is assisted by molecular chaperones in attaining its precise folded/highly...

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Hlavní autoři: Kulkarni, Prakash, Rajagopalan, Krithika, Yeater, David, Getzenberg, Robert H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472416/
https://ncbi.nlm.nih.gov/pubmed/21445877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23115
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