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The Energy Computation Paradox and ab initio Protein Folding

The routine prediction of three-dimensional protein structure from sequence remains a challenge in computational biochemistry. It has been intuited that calculated energies from physics-based scoring functions are able to distinguish native from nonnative folds based on previous performance with sma...

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Detalhes bibliográficos
Main Authors: Faver, John C., Benson, Mark L., He, Xiao, Roberts, Benjamin P., Wang, Bing, Marshall, Michael S., Sherrill, C. David, Merz, Kenneth M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081830/
https://ncbi.nlm.nih.gov/pubmed/21541343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018868
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