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Evolutionarily Conserved Network Properties of Intrinsically Disordered Proteins

BACKGROUND: Intrinsically disordered proteins (IDPs) lack a stable tertiary structure in isolation. Remarkably, however, a substantial portion of IDPs undergo disorder-to-order transitions upon binding to their cognate partners. Structural flexibility and binding plasticity enable IDPs to interact w...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rangarajan, Nivedita, Kulkarni, Prakash, Hannenhalli, Sridhar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431869/
https://ncbi.nlm.nih.gov/pubmed/25974317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126729
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