Intrinsically disordered proteins and conformational noise: Implications in cancer

Intrinsically disordered proteins, IDPs, are proteins that lack a rigid 3D structure under physiological conditions, at least in vitro. Despite the lack of structure, IDPs play important roles in biological processes and transition from disorder to order upon binding to their targets. With multiple...

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Autori principali: Mahmoudabadi, Gita, Rajagopalan, Krithika, Getzenberg, Robert H., Hannenhalli, Sridhar, Rangarajan, Govindan, Kulkarni, Prakash
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
Soggetti:
Perspective
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570512/
https://ncbi.nlm.nih.gov/pubmed/23255110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23178
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