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Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1

Activation-induced cytidine deaminase (AID) is a molecule central to initiating class switch recombination, somatic hypermutation, and gene conversion of Ig genes. However, its mechanism to initiate these genetic alterations is still unclear. AID can convert cytosine to uracil on either mRNA or DNA...

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Bibliografische gegevens
Hoofdauteurs: Ito, Satomi, Nagaoka, Hitoshi, Shinkura, Reiko, Begum, Nasim, Muramatsu, Masamichi, Nakata, Mikiyo, Honjo, Tasuku
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2004
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC357037/
https://ncbi.nlm.nih.gov/pubmed/14769937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307335101
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