Structure of the receptor-binding domain of human thrombopoietin determined by complexation with a neutralizing antibody fragment

The cytokine thrombopoietin (TPO), the ligand for the hematopoietic receptor c-Mpl, acts as a primary regulator of megakaryocytopoiesis and platelet production. We have determined the crystal structure of the receptor-binding domain of human TPO (hTPO(163)) to a 2.5-Å resolution by complexation with...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Feese, Michael D., Tamada, Taro, Kato, Yoichi, Maeda, Yoshitake, Hirose, Masako, Matsukura, Yasuko, Shigematsu, Hideki, Muto, Takanori, Matsumoto, Atsushi, Watarai, Hiroshi, Ogami, Kinya, Tahara, Tomoyuki, Kato, Takashi, Miyazaki, Hiroshi, Kuroki, Ryota
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2004
Θέματα:
Biological Sciences
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC357010/
https://ncbi.nlm.nih.gov/pubmed/14769915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308530100
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια