Structure of the receptor-binding domain of human thrombopoietin determined by complexation with a neutralizing antibody fragment

The cytokine thrombopoietin (TPO), the ligand for the hematopoietic receptor c-Mpl, acts as a primary regulator of megakaryocytopoiesis and platelet production. We have determined the crystal structure of the receptor-binding domain of human TPO (hTPO(163)) to a 2.5-Å resolution by complexation with...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Feese, Michael D., Tamada, Taro, Kato, Yoichi, Maeda, Yoshitake, Hirose, Masako, Matsukura, Yasuko, Shigematsu, Hideki, Muto, Takanori, Matsumoto, Atsushi, Watarai, Hiroshi, Ogami, Kinya, Tahara, Tomoyuki, Kato, Takashi, Miyazaki, Hiroshi, Kuroki, Ryota
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC357010/
https://ncbi.nlm.nih.gov/pubmed/14769915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308530100
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados