RNF4 is required for DNA double-strand break repair in vivo

Unrepaired DNA double-strand breaks (DSBs) cause genetic instability that leads to malignant transformation or cell death. Cells respond to DSBs with the ordered recruitment of signaling and repair proteins to the sites of DNA lesions. Coordinated protein SUMOylation and ubiquitylation have crucial...

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書誌詳細
主要な著者: Vyas, R, Kumar, R, Clermont, F, Helfricht, A, Kalev, P, Sotiropoulou, P, Hendriks, I A, Radaelli, E, Hochepied, T, Blanpain, C, Sablina, A, van Attikum, H, Olsen, J V, Jochemsen, A G, Vertegaal, A C O, Marine, J-C
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2013
主題:
Original Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569989/
https://ncbi.nlm.nih.gov/pubmed/23197296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.145
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https://ncbi.nlm.nih.gov/pmc/articles/PMC3569989/
https://ncbi.nlm.nih.gov/pubmed/23197296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.145

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