Učitavanje...
Current understanding of LRRK2 in Parkinson's disease: biochemical and structural features and inhibitor design
Since leucine-rich repeat kinase 2 (LRRK2) was linked to Parkinson's disease in 2004, kinase activity of LRRK2 has been believed to play a critical role in the pathogenesis of Parkinson's disease. As a result, identification of LRRK2 inhibitors has been a focus for drug discovery. However,...
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| Glavni autori: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3569718/ https://ncbi.nlm.nih.gov/pubmed/22924508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.12.110 |
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