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Nicotine Promotes Survival of Cells Expressing Amyloid Precursor Protein and Presenilin: Implication for Alzheimer’s Disease

Amyloid-β protein (Aβ) accumulation is one of the major hallmarks of Alzheimer’s disease (AD) and plays a crucial role in its pathogenesis. Cellular models whereby amyloid precursor protein (APP) is highly expressed are commonly used to test the efficacy of novel neuroprotective compounds. In additi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Brown, Dwayne, Ramlochansingh, Carlana, Manaye, Kebreten F., Tizabi, Yousef
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569508/
https://ncbi.nlm.nih.gov/pubmed/23313596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2012.12.046
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