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Nicotine Promotes Survival of Cells Expressing Amyloid Precursor Protein and Presenilin: Implication for Alzheimer’s Disease
Amyloid-β protein (Aβ) accumulation is one of the major hallmarks of Alzheimer’s disease (AD) and plays a crucial role in its pathogenesis. Cellular models whereby amyloid precursor protein (APP) is highly expressed are commonly used to test the efficacy of novel neuroprotective compounds. In additi...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3569508/ https://ncbi.nlm.nih.gov/pubmed/23313596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2012.12.046 |
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