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Nicotine Promotes Survival of Cells Expressing Amyloid Precursor Protein and Presenilin: Implication for Alzheimer’s Disease

Amyloid-β protein (Aβ) accumulation is one of the major hallmarks of Alzheimer’s disease (AD) and plays a crucial role in its pathogenesis. Cellular models whereby amyloid precursor protein (APP) is highly expressed are commonly used to test the efficacy of novel neuroprotective compounds. In additi...

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Bibliographische Detailangaben
Hauptverfasser: Brown, Dwayne, Ramlochansingh, Carlana, Manaye, Kebreten F., Tizabi, Yousef
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569508/
https://ncbi.nlm.nih.gov/pubmed/23313596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2012.12.046
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